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Immunohistochemical study of the PTEN/AKT pathway and the PTEN effects on E-cadherin expression in canine and feline mammary tumors

The PTEN/AKT pathway plays a key role in several biological effects such as cell metabolism, cell proliferation and cell survival. For these reason, this system is directly implicated in tumor growth and aggressiveness. Aberrant activation of this pathway is associated with several malignancies in h...

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Format: Doctoral Thesis
Language: Italian
Published: Pisa University 2014
Online Access: Embargoed access