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Effect of anti-TNF therapy on T cell activation and effector functions in patients with chronic inflammatory diseases

TNF-blocking therapy is successfully used in the treatment of immune-mediated and inflammatory diseases. Although the inhibition of inflammatory pathways in target tissues by anti-TNF therapy has been clearly described, the impact of TNF-blockade on peripheral T cell responses in humans is still unc...

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Main Author: Raeli,
Format: Doctoral Thesis
Language: English
Published: Università degli Studi di Milano-Bicocca 2009
Online Access: http://hdl.handle.net/10281/10634 Open access