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STUDY OF THE ALTERNATIVE ISOFORMS OF PRDM16 PROTEIN AND OF THEIR POSSIBLE ROLE IN LEUKEMOGENESIS

PRDM16 is a member of PRDM gene family, composed of 17 genes. All the PRDM genes so far connected to cancer have (at least) two isoforms, which differ by the presence (PR+) or absence (PR-) of the PR domain that is related to SET domain of histone lysine methyltransferases (HKMTases). In cancer cell...

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Main Author: WIERZBICKA
Other Authors: MALGORZATA
Format: Doctoral Thesis
Language: English
Published: Università degli Studi di Milano 2013
Online Access: http://hdl.handle.net/2434/219070 Restricted access