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ACID SPHINGOMYELINASE AND MITOCHONDRIA: A NEW LINKIN CHEMOTHERAPEUTIC DRUGS INDUCED APOPTOSIS

Melanoma is the most aggressive form of skin cancer and is notoriously resistant to all current modalities of cancer therapy. Malignant melanomas are composed of subpopulations of cells characterized by highly heterogeneity. This clonal heterogeneity of tumor cells accounts for the existence or app...

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Main Author: CAZZATO
Other Authors: DENISE
Format: Doctoral Thesis
Language: English
Published: Università degli Studi di Milano 2013
Online Access: http://hdl.handle.net/2434/214971 Restricted access