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SYNTHESIS OF FUCOSE-BASED LIGANDS FOR DC-SIGN.

DC-SIGN is a C-type lectin that is expressed in dendritic cells and that is involved in a number of infection processes such as HIV or Ebola. Within the scope of this work a library of monovalent, fucose-based ligands was synthesised to block DC-SIGN. The structures originate from three scaffolds co...

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Main Author: DOKNIC
Other Authors: DANIELA
Format: Doctoral Thesis
Language: English
Published: Università degli Studi di Milano 2012
Online Access: http://hdl.handle.net/2434/203241 Restricted access