SYNTHESIS OF FUCOSE-BASED LIGANDS FOR DC-SIGN.
DC-SIGN is a C-type lectin that is expressed in dendritic cells and that is involved in a number of infection processes such as HIV or Ebola. Within the scope of this work a library of monovalent, fucose-based ligands was synthesised to block DC-SIGN. The structures originate from three scaffolds co...
Università degli Studi di Milano