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FLUCTUATION OF ESTROGEN RECEPTOR TRANSCRIPTIONAL ACTIVITY IN PHYSIOLOGICAL CONDITIONS: FUNCTIONAL CONSEQUENCES

We have studied the dynamics of estrogen receptor (ER) activity in whole living animal through the application of in vivo imaging to the ERE-Luc mice, characterized by the hormone-inducible, generalized, expression of the ERE-driven luciferase gene. The analysis shows that ER transcriptional activi...

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Main Author: STELL
Other Authors: ALESSIA
Format: Doctoral Thesis
Language: English
Published: Università degli Studi di Milano 2010
Online Access: http://hdl.handle.net/2434/150095 Open access